• PDB 3OY1 | dpdb_hjoge1ayHighly Selective c-Jun N-Terminal Kinase (JNK) 2 and 3 Inhibitors with In Vitro CNS-like Pharmacokinetic PropertiesUpdated Oct 3, 2026
• PDB 4O09 | dpdb_y9lkpjd4Identification of novel HSP90 / isoform selective inhibitors using structure-based drug design. Demonstration of potential utility in treating CNS disorders such as Huntington s diseaseUpdated Oct 3, 2026
• PDB 4O04 | dpdb_04an6y4yIdentification of novel HSP90/isoform selective inhibitors using structure-based drug design. Demonstration of potential utility in treating CNS disorders such as Huntington's diseaseUpdated Oct 2, 2026
• PDB 4N00 | dpdb_3xom6qskDiscovery of 7-THP chromans: BACE1 inhibitors that reduce A-beta in the CNSUpdated Oct 1, 2026
• PDB 4O05 | dpdb_okq9akqwIdentification of novel HSP90/isoform selective inhibitors using structure-based drug design. Demonstration of potential utility in treating CNS disorders such as Huntington's diseaseUpdated Oct 1, 2026
• PDB 4O07 | dpdb_13los4uuIdentification of novel HSP90/isoform selective inhibitors using structure-based drug design. Demonstration of potential utility in treating CNS disorders such as Huntington's diseaseUpdated Sep 30, 2026
• PDB 4RD7 | dpdb_hs38p9p8The crystal structure of a Cupin 2 conserved barrel domain protein from Salinispora arenicola CNS-205Updated Sep 30, 2026
• PDB 4O0B | dpdb_dikoqp6gIdentification of novel HSP90/isoform selective inhibitors using structure-based drug design. Demonstration of potential utility in treating CNS disorders such as Huntington's diseaseUpdated Sep 27, 2026