Info
8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors
- PDB
- 4R5N
- Resolution
- 1.8 Å
- Method
- X-ray crystallography
- Space group
- C 2 2 21
- Organism
- Homo sapiens
Files
Models
| Model | ||
|---|---|---|
 Deposited modelAug 10, 2026 | 0.186 | 0.23 |
| Rerefined modelAug 10, 2026 | 0.189 | 0.239 |
| Ensemble refinement modelAug 10, 2026 | 0.156 | 0.197 |
| qFit modelAug 10, 2026 | 0.151 | 0.192 |