Info

Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R273H mutant bound to DNA: R273H-DNA

PDB
7B4A
Resolution
1.9 Å
Method
X-ray crystallography
Space group
C 1 2 1
Organism
Homo sapiens; synthetic construct

Files

Models

Model
Deposited modelAug 11, 20260.2070.254
Rerefined modelAug 11, 20260.240.283
Ensemble refinement modelAug 11, 20260.2260.262
qFit modelAug 11, 20260.2150.257