Info
Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R282W mutant bound to DNA and MQ: R282W-DNA-MQ
- PDB
- 7B4E
- Resolution
- 1.57 Å
- Method
- X-ray crystallography
- Space group
- C 1 2 1
- Organism
- Homo sapiens; synthetic construct
Files
Models
| Model | ||
|---|---|---|
 Deposited modelAug 13, 2026 | 0.166 | 0.201 |
| qFit modelAug 13, 2026 | 0.145 | 0.185 |
| Ensemble refinement modelAug 13, 2026 | 0.169 | 0.213 |