Info
Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R282W mutant bound to DNA: R282W-MQ (I)
- PDB
- 7B4F
- Resolution
- 1.78 Å
- Method
- X-ray crystallography
- Space group
- C 1 2 1
- Organism
- Homo sapiens; synthetic construct
Files
Models
| Model | ||
|---|---|---|
 Deposited modelAug 11, 2026 | 0.155 | 0.195 |
| Rerefined modelAug 11, 2026 | 0.165 | 0.215 |
| Ensemble refinement modelAug 11, 2026 | 0.147 | 0.199 |
| qFit modelAug 11, 2026 | 0.152 | 0.204 |