Info
Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R273C/S240R double mutant bound to DNA and MQ: R273C/S240R-DNA-MQ
- PDB
- 7B4D
- Resolution
- 1.85 Å
- Method
- X-ray crystallography
- Space group
- C 1 2 1
- Organism
- Homo sapiens; synthetic construct
Files
Models
| Model | ||
|---|---|---|
 Deposited modelAug 11, 2026 | 0.168 | 0.204 |
| Rerefined modelAug 11, 2026 | 0.176 | 0.223 |
| Ensemble refinement modelAug 11, 2026 | 0.174 | 0.219 |
| qFit modelAug 11, 2026 | 0.19 | 0.243 |