Deposited model

PDB 4LH4|dpdb_0h44rr1w

Deposited model

Dual inhibition of HIV-1 replication by Integrase-LEDGF allosteric inhibitors is predominant at post-integration stage during virus production rather than at integration

Program
REFMAC 5.7.0032
Model type
Deposited
Purpose
Reference
Authors
Ruff, M., Levy, N., Eiler, S.
Atoms
1,190
Residues
131
Protein chains
1
Unmodeled fraction
28.02%
Ligand
MG

Evaluations

R-work
0.200
R-free
0.247
Clashscore
18.2

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Integrase182
  • Human immunodeficiency virus 111676
  • ConstructUNP residues 50-212
  • MutationF185K

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations