Deposited model

PDB 6HRT|dpdb_1019qgjp

Deposited model

CRYSTAL STRUCTURE OF BTK KINASE DOMAIN COMPLEXED WITH 12-(6-tert-butyl-8-fluoro-1-oxo-phthalazin-2-yl)-9-hydroxy-6-methyl-4-[[5-(morpholine-4-carbonyl)-2-pyridyl]amino]-6-azatricyclo[9.4.0.02,7]pentadeca-1(15),2(7),3,11,13-pentaen-5-one

Program
REFMAC 5.5.0072
Model type
Deposited
Purpose
Reference
Authors
Kuglstatter, A., Janson, C.
Atoms
2,573
Residues
263
Protein chains
1
Unmodeled fraction
7.07%

Evaluations

R-work
0.177
R-free
0.201
Clashscore
4.9

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase BTK283
  • MutationsM489A R492A E624A K625A

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations