Deposited model

PDB 3VS6|dpdb_1s8seebp

Deposited model

Crystal structure of HCK complexed with a pyrazolo-pyrimidine inhibitor tert-butyl {4-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl}carbamate

Program
PHENIX 1.7.3_928)
Model type
Deposited
Purpose
Reference
Authors
Kuratani, M., Honda, K., Tomabechi, Y., Toyama, M., Handa, N., Yokoyama, S.
Atoms
7,398
Residues
870
Protein chains
2
Unmodeled fraction
4.19%
Ligand
CA

Evaluations

R-work
0.230
R-free
0.280
Clashscore
8.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase HCK454
  • ConstructUNP residues 81-526
  • MutationsQ528E Q529E Q530I

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations