Deposited model

PDB 3VS2|dpdb_1xiodkq8

Deposited model

Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Program
PHENIX 1.7.3_928)
Model type
Deposited
Purpose
Reference
Authors
Kuratani, M., Tomabechi, Y., Niwa, H., Parker, J.L., Handa, N., Yokoyama, S.
Atoms
7,189
Residues
865
Protein chains
2
Unmodeled fraction
4.74%
Ligand
CA

Evaluations

R-work
0.226
R-free
0.279
Clashscore
6.0

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase HCK454
  • ConstructUNP residues 81-526
  • MutationsQ528E Q529E Q530I

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations