Deposited model

PDB 1O5B|dpdb_1yhbwota

Deposited model

Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)

Program
X-PLOR 3.851
Model type
Deposited
Purpose
Reference
Authors
Katz, B.A., Luong, C., Ho, J.D., Somoza, J.R., Gjerstad, E., Tang, J., Williams, S.R., Verner, E., Mackman, R.L., Young, W.B., Sprengeler, P.A., Chan, H., Mortara, K., Janc, J.W., McGrath, M.E.
Atoms
2,419
Residues
253
Protein chains
2
Unmodeled fraction
8.33%

Evaluations

R-work
0.197
R-free
0.240
Clashscore
4.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Urokinase-type plasminogen activator23
  • ConstructSHORT CHAIN
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Urokinase-type plasminogen activator253
  • ConstructCATALYTIC DOMAIN
  • MutationsN145A/S190A

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations