Dynamic PDB
Log in

Rerefined model

PDB 7B4A|dpdb_23tamnen

Rerefined model

Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R273H mutant bound to DNA: R273H-DNA

Program
PHENIX 2.0_5824
Model type
Multiconformer
Purpose
Refinement
Atoms
4,209
Residues
410
Protein chains
3
Alternate-location fraction
6.59%
Ligands
FMT, ZN

Evaluations

R-work
0.240
R-free
0.282
Clashscore
6.0

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Cellular tumor antigen p53200
  • Constructp53 human DNA binding domain
  • MutationR273H
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
DNA target20—
  • Constructp53 DNA target
  • Mutations'

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations