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Deposited model

PDB 2C2Z|dpdb_2g7d229j

Deposited model

Crystal structure of caspase-8 in complex with aza-peptide Michael acceptor inhibitor

Program
CNS 1.1
Model type
Deposited
Purpose
Reference
Authors
Ganesan, R., Jelakovic, S., Ekici, O.D., Li, Z.Z., James, K.E., Asgian, J.L., Campbell, A.J., Mikolajczyk, J., Salvesen, G.S., Powers, J.C., Gruetter, M.G.
Atoms
2,300
Residues
245
Protein chains
3
Unmodeled fraction
9.26%

Evaluations

R-work
0.171
R-free
0.187
Clashscore
4.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
CASPASE-8 P18 SUBUNIT159
  • ConstructALPHA SUB-UNIT, RESIDUES 218-374
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
CASPASE-8 P10 SUBUNIT106
  • ConstructBETA-SUBUNIT, RESIDUES 376-479
Entity 3
MoleculeChainsLengthOrganismUniProtDetails
AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL) -14-[4-(3,4-DIHYDROQUINOLIN-1(2H)-YL)-4-OXOBUTANOYL] -11-[(1R)-1-HYDROXYETHYL]-5-(2-METHYLPROPYL)-3,6,9,12-TETRAOXO -1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN-16-OIC ACID5——

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations