Deposited model

PDB 6GQM|dpdb_30ugs4uh

Deposited model

Crystal structure of human c-KIT kinase domain in complex with a small molecule inhibitor, AZD3229

Program
BUSTER 2.11.6
Model type
Deposited
Purpose
Reference
Authors
Schimpl, M., Hardy, C.J., Ogg, D.J., Overman, R.C., Packer, M.J., Kettle, J.G., Anjum, R., Barry, E., Bhavsar, D., Brown, C., Campbell, A., Goldberg, K., Grondine, M., Guichard, S., Hunt, T., Jones, O., Li, X., Moleva, O., Pearson, S., Shao, W., Smith, A., Smith, J., Stead, D., Stokes, S., Tucker, M., Ye, Y.
Atoms
4,972
Residues
585
Protein chains
2
Unmodeled fraction
10.82%

Evaluations

R-work
0.203
R-free
0.230
Clashscore
1.4

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Mast/stem cell growth factor receptor Kit328
  • MutationsI563S V569S Y609Q L631S M651E I662H D768H R804N V825D C844S L890S H894Y L912D L923D

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations