Ensemble refinement model

PDB 5TQ3|dpdb_32gh9420

Ensemble refinement model

Design and Synthesis of a pan-JAK kinase inhibitor clinical candidate (PF-06263276) suitable for the treatment of inflammatory diseases of the lungs and skin

Program
PHENIX phenix.ensemble_refinement
Model type
Ensemble
Purpose
Refinement
Atoms
97,011
Residues
567
Protein chains
2
Alternate-location fraction
0%
Ligands
7GZ, PTR

Evaluations

R-work
0.170
R-free
0.245
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase JAK2304
  • ConstructUNP residues 837-1132
  • MutationsM1073S F1076S I1126V

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations