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Deposited model

PDB 3PTG|dpdb_4c6ifn50

Deposited model

Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor

Program
REFMAC 5.2.0019
Model type
Deposited
Purpose
Reference
Authors
Bowers, S., Truong, A.P., Neitz, J., Neitzel, M., Probst, G.D., Hom, R.K., Konradi, A.W., Sham, H.L., Toth, G., Pan, H., Yao, N., Artis, D.R., Brigham, E.F., Quinn, K.P., Sauer, J., Powell, K., Ruslim, L., Bard, F., Yednock, T.A., Griswold-Prenner, I.
Atoms
2,895
Residues
350
Protein chains
2
Unmodeled fraction
6.42%

Evaluations

R-work
0.244
R-free
0.316
Clashscore
19.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Mitogen-activated protein kinase 10363
  • ConstructUNP residues 40-401
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
C-Jun-amino-terminal kinase-interacting protein 111
  • ConstructUNP residues 157-167

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations