Ensemble refinement model

PDB 4DTG|dpdb_4qxzlcrz

Ensemble refinement model

Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model

Program
PHENIX 2.0_5824
Model type
Ensemble
Purpose
Refinement
Atoms
279,728
Residues
500
Protein chains
3
Alternate-location fraction
0%
Ligands
GOL, MES, PGE

Evaluations

R-work
0.195
R-free
0.235
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Humanized recombinant FAB fragment, FAB 2021, of a murine antibody, light chain219——
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Humanized recombinant FAB fragment, FAB 2021, of a murine antibody, heavy chain222——
Entity 3
MoleculeChainsLengthOrganismUniProtDetails
Tissue factor pathway inhibitor66
  • ConstructKunitz-type protease inhibitor domain 2 (UNP residues 119-178)

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations