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Deposited model

PDB 4RZV|dpdb_5jorwfpt

Deposited model

Crystal structure of the BRAF (R509H) kinase domain monomer bound to Vemurafenib

Program
PHENIX (phenix.refine
Model type
Deposited
Purpose
Reference
Authors
Wu, Y., Gavathiotis, E.
Atoms
4,318
Residues
532
Protein chains
2
Unmodeled fraction
5.34%

Evaluations

R-work
0.204
R-free
0.267
Clashscore
7.2

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Serine/threonine-protein kinase B-raf281
  • ConstructProtein kinase domain residues 443-723
  • MutationsR509H I543A I544S I551K Q562R L588N K630S F667E Y673S A688R L706S Q709R S713E L716E S720E P722S K723G

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations