Deposited model

PDB 3R21|dpdb_5o38kiii

Deposited model

Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (Part I)

Program
REFMAC 5.5.0109
Model type
Deposited
Purpose
Reference
Authors
Zhang, L., Fan, J., Chong, J.-H., Cesena, A., Tam, B., Gilson, C., Boykin, C., Wang, D., Marcotte, D., Le Brazidec, J.-Y., Aivazian, D., Piao, J., Lundgren, K., Hong, K., Vu, K., Nguyen, K.
Atoms
2,112
Residues
254
Protein chains
1
Unmodeled fraction
6.27%
Ligand
MG

Evaluations

R-work
0.258
R-free
0.305
Clashscore
21.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Serine/threonine-protein kinase 6271
  • Constructunp residues 126-391
  • MutationsT287D T288D

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations