Deposited model

PDB 4JVR|dpdb_6cvn9ngp

Deposited model

Co-crystal structure of MDM2 with inhibitor (2'S,3R,4'S,5'R)-N-(2-aminoethyl)-6-chloro-4'-(3-chloro-2-fluorophenyl)-2'-(2,2-dimethylpropyl)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxamide

Program
CNS
Model type
Deposited
Purpose
Reference
Authors
Huang, X., Gonzalez-Lopez de Turiso, F., Sun, D., Yosup, R., Bartberger, M.D., Beck, H.P., Cannon, J., Shaffer, P., Oliner, J.D., Olson, S.H., Medina, J.C.
Atoms
2,458
Residues
266
Protein chains
3
Unmodeled fraction
7.64%

Evaluations

R-work
0.256
R-free
0.270
Clashscore
31.4

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
E3 ubiquitin-protein ligase Mdm296
  • ConstructUNP residues 18-111

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations