Deposited model

PDB 4UF0|dpdb_6wqtwxbx

Deposited model

Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid.

Program
REFMAC 5.8.0073
Model type
Deposited
Purpose
Reference
Authors
Srikannathasan, V., Johansson, C., Gileadi, C., Tobias, K., Kopec, J., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Oppermann, U.
Atoms
7,696
Residues
882
Protein chains
2
Unmodeled fraction
7.74%
Ligands
FE2, MMK, ZN

Evaluations

R-work
0.149
R-free
0.215
Clashscore
4.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
HISTONE DEMETHYLASE UTY478
  • ConstructJMJC DOMAIN, RESIDUES 878-1347
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
HISTONE DEMETHYLASE UTY478
  • ConstructJMJC DOMAIN, RESIDUES 878-1347

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations