Deposited model

PDB 2V7A|dpdb_73z83e76

Deposited model

Crystal structure of the T315I Abl mutant in complex with the inhibitor PHA-739358

Program
REFMAC 5.2.0019
Model type
Deposited
Purpose
Reference
Authors
Modugno, M., Casale, E., Soncini, C., Rosettani, P., Colombo, R., Lupi, R., Rusconi, L., Fancelli, D., Carpinelli, P., Cameron, A.D., Isacchi, A., Moll, J.
Atoms
4,638
Residues
541
Protein chains
2
Unmodeled fraction
5.42%
Ligand
MG

Evaluations

R-work
0.207
R-free
0.246
Clashscore
5.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1286
  • ConstructKINASE DOMAIN, RESIDUES 229-512
  • MutationsYES

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations