Deposited model

PDB 4B05|dpdb_7cqtc4f6

Deposited model

Preclinical characterization of AZD3839, a novel clinical candidate BACE1 inhibitor for the treatment of Alzheimer Disease

Program
BUSTER 2.11.1
Model type
Deposited
Purpose
Reference
Authors
Jeppsson, F., Eketjall, S., Janson, J., Karlstrom, S., Gustavsson, S., Olsson, L.L., Radesater, A.C., Ploeger, B., Cebers, G., Kolmodin, K., Swahn, B.M., von Berg, S., Bueters, T., Falting, J.
Atoms
3,330
Residues
371
Protein chains
1
Unmodeled fraction
9.73%
Ligand
NA

Evaluations

R-work
0.178
R-free
0.215
Clashscore
1.2

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
BETA-SECRETASE 1411
  • ConstructRESIDUES 43-453
  • MutationsYES

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations