Deposited model

PDB 1O5E|dpdb_7l671b6s

Deposited model

Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)

Program
X-PLOR 3.851
Model type
Deposited
Purpose
Reference
Authors
Katz, B.A., Luong, C., Ho, J.D., Somoza, J.R., Gjerstad, E., Tang, J., Williams, S.R., Verner, E., Mackman, R.L., Young, W.B., Sprengeler, P.A., Chan, H., Mortara, K., Janc, J.W., McGrath, M.E.
Atoms
2,980
Residues
358
Protein chains
2
Unmodeled fraction
2.98%

Evaluations

R-work
0.198
R-free
0.227
Clashscore
5.4

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Serine protease hepsin114
  • Constructlight chain
  • MutationN67A
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Serine protease hepsin255
  • Constructheavy chain (catalytic domain)

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations