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Ensemble refinement model

PDB 5HI5|dpdb_7uzt26nk

Ensemble refinement model

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

Program
PHENIX 1.21.2_5419
Model type
Ensemble
Purpose
Refinement
Atoms
425,903
Residues
1,061
Protein chains
7
Alternate-location fraction
0%
Ligand
63Q

Evaluations

R-work
0.186
R-free
0.222
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Interleukin-17A132
  • ConstructUNP residues 24-155
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
CAT-2000 FAB heavy chain237——
Entity 3
MoleculeChainsLengthOrganismUniProtDetails
CAT-2000 light chain214——
Entity 4
MoleculeChainsLengthOrganismUniProtDetails
synthetic IL-17A inhibitor16——

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations