Deposited model

PDB 5HG8|dpdb_8c782dg5

Deposited model

EGFR (L858R, T790M, V948R) in complex with N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide

Program
CNX 2005
Model type
Deposited
Purpose
Reference
Authors
Gajiwala, K.S.
Atoms
2,716
Residues
300
Protein chains
1
Unmodeled fraction
8.81%
Ligand
634

Evaluations

R-work
0.208
R-free
0.213
Clashscore
5.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Epidermal growth factor receptor329
  • ConstructUNP residues 695-1022
  • MutationsL858R T790M V948R

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations