Deposited model

PDB 2QAB|dpdb_90h4meaw

Deposited model

Crystal Structure of Estrogen Receptor Alpha Ligand Binding Domain Mutant 537S Complexed with an Ethyl Indazole Compound

Program
REFMAC 5.2.0005
Model type
Deposited
Purpose
Reference
Authors
Nettles, K.W., Bruning, J.B., Nowak, J., Sharma, S.K., Hahm, J.B., Shi, Y., Kulp, K., Hochberg, R.B., Zhou, H., Katzenellenbogen, J.A., Katzenellenbogen, B.S., Kim, Y., Joachmiak, A., Greene, G.L.
Atoms
4,099
Residues
501
Protein chains
4
Unmodeled fraction
7.56%

Evaluations

R-work
0.224
R-free
0.270
Clashscore
8.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Estrogen receptor258
  • ConstructSteroid-binding region, residues 298-554
  • MutationY537S
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
nuclear receptor coactivator 213—

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations