Deposited model

PDB 5AA9|dpdb_bl9wcmqr

Deposited model

Structure of L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).

Program
CNX 2005
Model type
Deposited
Purpose
Reference
Authors
McTigue, M., Deng, Y.-L., Liu, W., Brooun, A., Stewart, A.
Atoms
2,564
Residues
296
Protein chains
1
Unmodeled fraction
9.48%

Evaluations

R-work
0.200
R-free
0.237
Clashscore
10.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
ALK TYROSINE KINASE RECEPTOR327
  • ConstructTYROSINE KINASE DOMAIN, UNP RESIDUES 1093-1411
  • MutationsYES

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations