Deposited model

PDB 7B4B|dpdb_bqotchn0

Deposited model

Structural basis of reactivation of oncogenic p53 mutants by a small molecule: methylene quinuclidinone (MQ). Human p53DBD-R273C mutant bound to MQ: R273C-MQ (I)

Program
PHENIX 1.18.2-3874
Model type
Deposited
Purpose
Reference
Authors
Degtjarik, O., Rozenberg, H., Shakked, Z.
Atoms
7,039
Residues
756
Protein chains
4
Unmodeled fraction
5.5%
Ligands
QN8, QNN, ZN

Evaluations

R-work
0.179
R-free
0.218
Clashscore
4.2

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Cellular tumor antigen p53200
  • Constructp53 human DNA binding domain
  • MutationR273C

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations