Deposited model

PDB 2BT0|dpdb_c113oxo9

Deposited model

Novel, potent small molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design

Program
REFMAC 5.1.24
Model type
Deposited
Purpose
Reference
Authors
Dymock, B.W., Barril, X., Brough, P.A., Cansfield, J.E., Massey, A., McDonald, E., Hubbard, R.E., Surgenor, A., Roughley, S.D., Webb, P., Workman, P., Wright, L., Drysdale, M.J.
Atoms
3,836
Residues
418
Protein chains
2
Unmodeled fraction
11.06%

Evaluations

R-work
0.202
R-free
0.244
Clashscore
3.9

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
HEAT SHOCK PROTEIN HSP90-ALPHA235
  • ConstructN-TERMINAL DOMAIN, RESIDUES 1-235

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations