Deposited model

PDB 3D15|dpdb_cwm82v66

Deposited model

Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-(3-chloro-phenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)- ethyl]-thiazol-2-yl}-urea [SNS-314]

Program
REFMAC 5.2.0005
Model type
Deposited
Purpose
Reference
Authors
Elling, R.A., Bui, M., Allen, D.A., Oslob, J.D., Romanowski, M.J.
Atoms
2,238
Residues
256
Protein chains
1
Unmodeled fraction
5.88%

Evaluations

R-work
0.234
R-free
0.287
Clashscore
8.1

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
serine/threonine kinase 6272
  • ConstructAurora-A kinase domain, UNP residues 116-382
  • MutationsN186G K240R M302L

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations