Deposited model

PDB 5EDR|dpdb_d00pndh2

Deposited model

EGFR kinase (T790M/L858R) with inhibitor compound 27: ~{N}-(1~{H}-indazol-3-yl)-7,7-dimethyl-2-(2-methylpyrazol-3-yl)-5~{H}-furo[3,4-d]pyrimidin-4-amine

Program
BUSTER 2.11.5
Model type
Deposited
Purpose
Reference
Authors
Eigenbrot, C., Yu, C.
Atoms
2,493
Residues
299
Protein chains
1
Unmodeled fraction
9.67%

Evaluations

R-work
0.191
R-free
0.215
Clashscore
2.9

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Epidermal growth factor receptor331
  • MutationsT790M L858R E865A E866A K867A

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations