Ensemble refinement model

PDB 5LN2|dpdb_dce87jf0

Ensemble refinement model

Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument

Program
PHENIX phenix.ensemble_refinement
Model type
Ensemble
Purpose
Refinement
Atoms
25,410
Residues
95
Protein chains
1
Alternate-location fraction
0%
Ligands
6ZT, CL, SO4

Evaluations

R-work
0.180
R-free
0.241
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
E3 ubiquitin-protein ligase Mdm296
  • ConstructN-terminal domain, p53 binding domain

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations