Ensemble refinement model

PDB 4I5M|dpdb_dwkb3wz9

Ensemble refinement model

Selective & Brain-Permeable Polo-like Kinase-2 (Plk-2) Inhibitors that Reduce -Synuclein Phosphorylation in Rat Brain

Program
PHENIX phenix.ensemble_refinement
Model type
Ensemble
Purpose
Refinement
Atoms
69,505
Residues
273
Protein chains
1
Alternate-location fraction
0%
Ligand
R78

Evaluations

R-work
0.235
R-free
0.281
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Serine/threonine-protein kinase PLK2308
  • ConstructPLK2 kinase domain
  • MutationsC83S V87T A119S A216S C259A C291S L335T

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations