Ensemble refinement model

PDB 8G2M|dpdb_ehujs7me

Ensemble refinement model

The tumor activated anti-CTLA-4 monoclonal antibody XTX101 demonstrates tumor-growth inhibition and tumor-selective pharmacodynamics in mouse models of cancer

Program
PHENIX 1.21.2_5419
Model type
Ensemble
Purpose
Refinement
Atoms
244,149
Residues
431
Protein chains
3
Alternate-location fraction
0%
Ligand
CIT

Evaluations

R-work
0.166
R-free
0.205
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
masking peptide9
  • Peptide display vector fth1160651
——
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Heavy chain of humanized IgG220——
Entity 3
MoleculeChainsLengthOrganismUniProtDetails
Light chain of humanized IgG202——

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations