Ensemble refinement model

PDB 1O5F|dpdb_eulk018e

Ensemble refinement model

Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA)

Program
PHENIX 1.21.2_5419
Model type
Ensemble
Purpose
Refinement
Atoms
143,164
Residues
358
Protein chains
2
Alternate-location fraction
0%
Ligand
CR9

Evaluations

R-work
0.161
R-free
0.209
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Serine protease hepsin114
  • Constructlight chain
  • MutationN67A
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Serine protease hepsin255
  • Constructheavy chain (catalytic domain)

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations