Deposited model

PDB 6GI6|dpdb_f820gjcr

Deposited model

Crystal structure of the ACVR1 (ALK2) kinase in complex with a Quinazolinone based ALK2 inhibitor with a 5-methyl core.

Program
PHENIX 1.13-2998
Model type
Deposited
Purpose
Reference
Authors
Williams, E., Hudson, L., Bezerra, G.A., Sorrell, F., Mahajan, P., Kupinska, K., Hoelder, S., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N.
Atoms
2,583
Residues
298
Protein chains
1
Unmodeled fraction
1%

Evaluations

R-work
0.213
R-free
0.263
Clashscore
7.3

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Activin receptor type-1301
  • MutationQ207D

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations