Deposited model

PDB 5AA8|dpdb_fqd8bcyy

Deposited model

Structure of C1156Y,L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).

Program
CNX 2005
Model type
Deposited
Purpose
Reference
Authors
McTigue, M., Deng, Y.-L., Liu, W., Brooun, A., Stewart, A.
Atoms
2,533
Residues
293
Protein chains
1
Unmodeled fraction
10.4%

Evaluations

R-work
0.209
R-free
0.233
Clashscore
12.4

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
ALK TYROSINE KINASE RECEPTOR327
  • ConstructTYROSINE KINASE DOMAIN, RESIDUES 1093-1411
  • MutationsYES

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations