Deposited model

PDB 5HG7|dpdb_fs1d7x4l

Deposited model

EGFR (L858R, T790M, V948R) in complex with 1-{(3R,4R)-3-[5-Chloro-2-(1-methyl-1H-pyrazol-4-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yloxymethyl]-4-methoxy-pyrrolidin-1-yl}propenone (PF-06459988)

Program
CNX 2005
Model type
Deposited
Purpose
Reference
Authors
Gajiwala, K.S.
Atoms
2,505
Residues
280
Protein chains
1
Unmodeled fraction
14.89%
Ligand
630

Evaluations

R-work
0.215
R-free
0.246
Clashscore
5.8

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Epidermal growth factor receptor329
  • ConstructUNP residues 695-1022
  • MutationsL858R T790M V948R

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations