Deposited model

PDB 3D2K|dpdb_fuylljei

Deposited model

Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with [7-(2-{2-[3-(3-chloro-phenyl)-ureido]-thiazol-5-yl}-ethylamino)-pyrazolo[4,3-d]pyrimidin-1-yl]-acetic acid

Program
REFMAC 5.2.0005
Model type
Deposited
Purpose
Reference
Authors
Elling, R.A., Oslob, J.D., Yu, C., Romanowski, M.J.
Atoms
2,092
Residues
245
Protein chains
1
Unmodeled fraction
9.93%

Evaluations

R-work
0.218
R-free
0.273
Clashscore
7.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
serine/threonine kinase 6272
  • ConstructAurora A kinase domain, UNP residues 116-382
  • MutationsN186G K240R M302L

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations