qFit model

PDB 5WEV|dpdb_g64qbvkz

qFit model

Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model

Program
Phenix 2.0_5824
Model type
Multiconformer
Purpose
Model Building
Atoms
4,392
Residues
293
Protein chains
1
Alternate-location fraction
73.04%
Ligands
9ZS, PTR

Evaluations

R-work
0.148
R-free
0.178
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase JAK2319
  • ConstructUNP residues 833-1132

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations