Deposited model

PDB 5AEP|dpdb_ggx7djlj

Deposited model

Novel pyrrole carboxamide inhibitors of JAK2 as potential treatment of myeloproliferative disorders

Program
REFMAC 5.6.0117
Model type
Deposited
Purpose
Reference
Authors
Canevari, G., Bertrand, J., Brasca, M.G., Nesi, M., Amboldi, N., Avanzi, N., Bindi, S., Casero, D., Ciomei, M., Colombo, N., Cribioli, S., Fachin, G., Felder, E.R., Galvani, A., Isacchi, A., Motto, I., Panzeri, A., Gnocchi, P., Donati, D.
Atoms
2,588
Residues
289
Protein chains
1
Unmodeled fraction
3.02%

Evaluations

R-work
0.171
R-free
0.213
Clashscore
6.2

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
TYROSINE-PROTEIN KINASE JAK2298
  • ConstructKINASE DOMAIN, RESIDUES 835-1132

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations