Deposited model

PDB 3VRZ|dpdb_gmnth9uq

Deposited model

Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor 1-[4-(4-amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-3-benzylurea

Program
PHENIX 1.7.3_928)
Model type
Deposited
Purpose
Reference
Authors
Kuratani, M., Tomabechi, Y., Handa, N., Yokoyama, S.
Atoms
7,258
Residues
861
Protein chains
2
Unmodeled fraction
5.18%
Ligand
CA

Evaluations

R-work
0.239
R-free
0.267
Clashscore
4.0

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase HCK454
  • ConstructUNP residues 81-526
  • MutationsQ528E Q529E Q530I

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations