Deposited model

PDB 4R5N|dpdb_gn6oynhj

Deposited model

8-Tetrahydropyran-2-yl chromans: highly selective beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors

Program
REFMAC 5.8.0049
Model type
Deposited
Purpose
Reference
Authors
Vigers, G.P.A., Smith, D.
Atoms
3,438
Residues
393
Protein chains
1
Unmodeled fraction
3.2%
Ligand
NI

Evaluations

R-work
0.186
R-free
0.230
Clashscore
2.9

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Beta-secretase 1406
  • Constructunp residues 57-453

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations