qFit model

PDB 5TO8|dpdb_gps8bk71

qFit model

Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency

Program
Phenix 2.0_5824
Model type
Multiconformer
Purpose
Model Building
Atoms
4,129
Residues
250
Protein chains
1
Alternate-location fraction
89.2%
Ligand
7FM

Evaluations

R-work
0.186
R-free
0.235
Clashscore
—

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Protein-tyrosine kinase 2-beta282
  • ConstructUNP Residues 414-692

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations