Deposited model

PDB 3IO7|dpdb_gza2ktnq

Deposited model

2-Aminopyrazolo[1,5-a]pyrimidines as potent and selective inhibitors of JAK2

Program
REFMAC
Model type
Deposited
Purpose
Reference
Authors
Zuccola, H.J., Ledeboer, M.W., Pierce, A.C.
Atoms
2,427
Residues
284
Protein chains
1
Unmodeled fraction
9.27%

Evaluations

R-work
0.199
R-free
0.294
Clashscore
5.7

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase JAK2313
  • ConstructJak kinase domain(UNP residue 842-1132)

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations