Deposited model

PDB 5H0H|dpdb_hmyr2ujh

Deposited model

Crystal structure of HCK complexed with a pyrrolo-pyrimidine inhibitor (S)-2-(((1r,4S)-4-(4-amino-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexyl)amino)-N,N,4-trimethylpentanamide

Program
PHENIX 1.9_1690
Model type
Deposited
Purpose
Reference
Authors
Tomabechi, Y., Kukimoto-Niino, M., Shirouzu, M.
Atoms
4,046
Residues
447
Protein chains
1
Unmodeled fraction
1.54%

Evaluations

R-work
0.185
R-free
0.224
Clashscore
3.6

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Tyrosine-protein kinase HCK454
  • ConstructUNP RESIDUES 81-526
  • MutationsQ523E Q524E Q525I

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations