Dynamic PDB
Log in

Deposited model

PDB 4RIY|dpdb_i08n3vla

Deposited model

Crystal structure of an EGFR/HER3 kinase domain heterodimer containing the cancer-associated HER3-E909G mutation

Program
PHENIX 1.9_1692)
Model type
Deposited
Purpose
Reference
Authors
Littlefield, P., Liu, L., Jura, N.
Atoms
9,122
Residues
1,134
Protein chains
4
Unmodeled fraction
15.5%
Ligands
ADP, ANP, MG

Evaluations

R-work
0.216
R-free
0.267
Clashscore
9.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Receptor tyrosine-protein kinase erbB-3326
  • ConstructKINASE DOMAIN, UNP residues 698-1020
  • MutationE909G
Entity 2
MoleculeChainsLengthOrganismUniProtDetails
Epidermal growth factor receptor345
  • ConstructKINASE DOMAIN, UNP residues 682-1022
  • MutationsV924R F973A L977A

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations