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Rerefined model

PDB 4ZYI|dpdb_inmo5y8i

Rerefined model

Discovery of NVP-CGM097 - a highly potent and selective MDM2 inhibitor undergoing phase 1 clinical trials in p53wt tumors: Hdm2 (MDM2) complexed with cpd2

Program
PHENIX 2.0_5824
Model type
Multiconformer
Purpose
Refinement
Atoms
844
Residues
90
Protein chains
1
Alternate-location fraction
0%
Ligands
4TH, CL

Evaluations

R-work
0.222
R-free
0.243
Clashscore
12.6

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
E3 ubiquitin-protein ligase Mdm296
  • ConstructN-TERMINAL DOMAIN, P53-BINDING DOMAIN, UNP residues 17-111

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations