Deposited model

PDB 4HZT|dpdb_izqw5wm0

Deposited model

Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates

Program
REFMAC 5.5.0109
Model type
Deposited
Purpose
Reference
Authors
Yao, N., Brecht, E.
Atoms
3,528
Residues
393
Protein chains
1
Unmodeled fraction
3.2%
Ligand
ZN

Evaluations

R-work
0.198
R-free
0.256
Clashscore
8.5

Macromolecules

The same in every model of this entry.

Entity 1
MoleculeChainsLengthOrganismUniProtDetails
Beta-secretase 1406
  • Constructunp residues 57-453

Data

L0 Raw
L1 Processed
L2 Models
L3 Evaluations